The oratory of Sant’ Andrea share the same square of the church of Santa Maria Maggiore and it was built between the XII and XIII century: of modest size, it was characterized by a cross vault; the Venerable Confraternity of Sant’ Andrea used to meet here, they also managed the nearby hospital and took care of the burial of the dead in the front garden.

The facade was originally decorated with a painting depicting the “Giudizio Finale”, today just few traces remain near the bell tower. The oratory was completely restored between the 17th and 18th centuries, with the elimination of the cross vault and the addition of the Baroque main altar.